Our paper on DNA polymerase actively displacing single-stranded DNA-binding proteins during replication has been published in Nature Communications! Using single-molecule studies and MD simulations, we revealed how DNA polymerase coordinates with SSBs to ensure efficient replication.
News & Announcements
Latest updates from my research and academic journey
Excited to be awarded the prestigious Damon Runyon Fellowship and been named as HHMI-Damon Runyon Fellow at UC Berkeley!
Excited to join Prof. Carlos Bustamante's lab at UC Berkeley/HHMI to study viral DNA packaging motors!
Our paper on DNA polymerase exchange during replication has been published in Nature Communications! Featured in The-Scientist and BioArt.
Excited to defend my PhD thesis! Congrats Dr. Xu.
Our paper is online in Nucleic Acids Research about bacteriophage T7 single-stranded DNA-binding protein (gp2.5) dynamics! We directly visualized T7 gp2.5 binding to ssDNA at the single-molecule level, showing how it reduces DNA contour length and suppresses secondary structure formation in a force-dependent manner.